产品货号：
Z35713
中文名称：
Peroxiredoxin 2/PRDX2抗体
英文名称：
Anti-Peroxiredoxin 2/PRDX2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Peroxiredoxin 2/PRDX2 Antibody |
| 指标别名 | NKEF B;NKEFB;peroxiredoxin 2;PRDX2;PRP;PRX II;PRX2;PRXII;TDPX1;Thioredoxin peroxidase 1;TSA |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,FCM |
| 基因名称 | PRDX2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human Peroxiredoxin 2 |
| 实际分子量 | 22KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | PRDX2(peroxiredoxin 2) also known as NKEFB,PRP,PRX2,PRXII or TPX1,is a protein that in humans is encoded by the PRDX2 gene.This gene encodes a member of the peroxiredoxin family of antioxidant enzymes,which reduce hydrogen peroxide and alkyl hydroperoxides.The encoded protein may play an antioxidant protective role in cells,and may contribute to the antiviral activity of CD8(+) T-cells.This protein may have a proliferative effect and play a role in cancer development or progression.The Prdx2 -/- mice were healthy in appearance and fertile.Choi et al.(2005) demonstrated that PRDX2 is a negative regulator of PDGF signaling.Prx II deficiency results in increased production of peroxide,enhanced activation of PDGF receptor and phospholipase C-gamma-1,and subsequently increased cell proliferation and migration in response to PDGF.PRX2 accounted for about half of the thioredoxin activity in parasite extracts,and PRX2 expression was increased in the presence of chloroquine,regardless of P.falciparum strain susceptibility to the drug. |
| Uniprot ID | P32119 |
| 基因名全称 | Peroxiredoxin-2 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:20～100ICC/IF 1:50～1:200 FC 1:50 |
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